Jordan Mason taken to locker room for x-rays after left shoulder injury

Photo by Jane Gershovich/Getty Images

The 49ers were already down Christian McCaffrey. Now they’re down Jordan Mason with Isaac Guerendo replacing him in the lineup.

The San Francisco 49ers entered Week 6 struggling with a host of injuries. On Thursday against the Seattle Seahawks, they suffered another notable injury. Running back Jordan Mason injured his left shoulder in the second quarter after claiming the NFL lead in rushing. Mason landed on his shoulder and was taken to the locker room for x-rays at the 9:37 mark in the quarter.

Isaac Guerendo replaced Mason who was already starting in place of an injured Christian McCaffrey. The 49ers are hoping to get McCaffrey back by November, but in the meantime, they’ll be short-handed at the position. Guerendo had four carries for six yards after Mason left the game.

Mason entered Thursday with 536 rushing yards, but had 65 on eight carries to move him past Derrick Henry for the league lead. The team announced him as questionable to return.

UPDATE: Mason was spotted on the sideline coming out of the two-minute warning at the end of the second quarter. His status remains uncertain, but he is still in pads and uniform and was wearing his helmet, so the 49ers likely are hoping he will return in the third quarter.